Biomedical Laboratory and Clinical Sciences (BLCS)

Check back on December 15th for Summer 2010 courses.

Metropolitan College

The following courses, offered at the Boston University School of Medicine (BUSM) in Boston's South End, are part of a program specializing in clinical research, biotechnology, and laboratory science.

All courses meet at BUSM. The "S" building is 801 Albany Street. The "R" and "L" Buildings are located at 715 Albany Street. Call the BLCS office at 617-638-5622 to request permission, confirm classroom, and obtain directions, or e-mail Constance Phillips at cphilli@bu.edu.

Medical Terminology II
GMS BT 106
Prereq: GMS BT 104 or consent of instructor. Continue building your medical vocabulary, learning the anatomy and diseases of the following systems: digestive, urinary, nervous, and integumentary (skin). 2 cr.

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Technical Writing for Clinical Research
GMS BT 210
Introduces students to the structure, content, and regulatory requirements of documents created for the clinical research industry. Reviews the FDA regulations and ICH guidances for drug, device and biologic documents, AMA Manual of Style Guidelines, and common industry standards. Students will learn to compose study abstracts, clinical protocols, informed consent forms, and clinical study reports. 4 cr.

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Introductory Biochemistry
GMS BT 305
Prereq: GMS BI 105 and GMS CH 101 or equivalent, or consent of instructor. Provides an overview of biochemistry to prepare students for advanced undergraduate or general graduate science courses. Topics covered include physical properties of biological molecules; structure and function of proteins, carbohydrates, lipids and nucleic acids; kinetics and mechanism of enzymatic catalysis; and metabolism. 4 cr.

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Clinical Laboratory Genetics I: Cytogenetics
GMS BT 406
Advanced course designed for those considering a clinical or research career in human genetics. Emphasis is on clinical cytogenetics (chromosome testing). Course covers types of chromosome abnormalities, methodology, nomenclature and clinical significance in pregnancy, birth defects, and cancer. Laboratory work includes basic blood culture, chromosome preparation, banding, identification, and karyotyping. Course provides updated review of latest cytogenetic methodology and applications, such as FISH, comparative genomic hybridization (CGH), and array CGH. Also available for graduate credit. Call the GMS office: 617-638-5120. 4 cr.

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Clinical Laboratory Genetics II: Molecular Genetics
GMS BT 407
Advanced course designed for those considering a clinical or research career in human genetics. Emphasis is on clinical molecular genetics (DNA testing). Course covers types of genetic abnormalities, methodology, nomenclature and clinical significance in pregnancy, birth defects, and cancer. Laboratory work includes basic blood extraction, DNA preparation, gel electrophoresis, capillary electrophoresis, sequencing, identification and karyotyping. Course provides updated review of latest molecular genetic methodology and applications, such as copy number analysis, chip based sequencing and next generation sequencing. 4 cr.

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Forensic Toxicology
GMS BT 450
Prereq: knowledge of biology and chemistry. Explores the role of toxicology in society both as a safeguard to prevent injury from environmental chemicals and a tool in the investigations of suspicious deaths. Case studies, guest speakers, and group discussions accompany lectures and demonstrations as students also explore the role of legal and medical communities as well as governmental agencies in dealing with issues. 4 cr.

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Advanced Cell Culture
GMS BT 484
Prereq: GMS BT 413 or equivalent, basic cell culture experience, or consent of instructor. Cell culture has become an indispensable tool for all areas of biomedical science. In this course, students develop the necessary routine by taking care of particular cell lines throughout the entire course. At the same time, students examine their cell lines using advanced techniques, such as transient and stable transfections, reporter gene assays, activation of signaling pathways, induction of cell differentiation, examination of cell cycle and apoptosis, fluorescent microscopy, and FACS analysis. At the end of the course, each group presents their findings during a poster session. 4 cr.

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Good Clinical Practices (GCP) in Clinical Research
GMS BT 560
Introduces the regulatory responsibilities of sponsors, monitors, and investigators conducting clinical trials. Practical information and exercises are designed for the clinical trial professional on procedures for ensuring GCP compliance from an industry perspective. Topics include identifying and selecting qualified investigators, obtaining ethical approval to enroll patients, and initiating sites successfully. Also covers issues related to collecting required regulatory documentation, verifying high quality data, maintaining study materials accountability, and reporting serious adverse events. Group discussions and guest speakers help students learn the practical skills used in the field. Permission required. Also available for graduate credit. Call the GMS office: 617-638-5120. 4 cr.

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Legal and Ethical Issues in Clinical Research
GMS BT 580
Students examine the development and implementation of regulatory as well as ethical issues involved with conducting clinical trials. Topics covered include: protection of human subjects, privacy and confidentiality, conflicts of interest, negativity toward clinical trials, research on vulnerable subjects, genetic testing, and genetic research. Also included are discussions of current ethical issues in clinical research within the media. Permission required. Also available for graduate credit. Call the GMS office: 617-638-5120. 2 cr.

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Biomed Externship
GMS BT 591/BT 592
Prereq: Meeting with Director and professional resume. Directed study for degree candidates only. Practical, hands-on experience in laboratory setting. Variable credits and fees, as arranged with Director Phillips. Permission required.

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